Gene name:
CDNF (ARMETL1) ;
Protein name:
Cerebral dopamine neurotrophic factor ;
Alternative:
Conserved dopamine neurotrophic factor ;ARMET-like protein 1 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.
Subcellular Location:
Secreted
Protein Attributes:
50:
MWCASPVAVV | AFCAGLLVSH | PVLTQGQEAG | GRPGADCEVC | KEFLNRFYKS |
100:
LIDRGVNFSL | DTIEKELISF | CLDTKGKENR | LCYYLGATKD | AATKILSEVT |
150:
RPMSVHMPAM | KICEKLKKLD | SQICELKYEK | TLDLASVDLR | KMRVAELKQI |
187:
LHSWGEECRA | CAEKTDYVNL | IQELAPKYAA | THPKTEL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Human Cerebral dopamine neurotrophic factor
ELISA Kit for Human Cerebral dopamine neurotrophic factor
ELISA Kit for Human Cerebral dopamine neurotrophic factor
CLIA Kit for Human Cerebral dopamine neurotrophic factor
CLIA Kit for Human Cerebral dopamine neurotrophic factor
CLIA Kit for Human Cerebral dopamine neurotrophic factor
Polyclonal Antibody for Human Cerebral dopamine neurotrophic factor
Polyclonal Antibody for Human Cerebral dopamine neurotrophic factor
Polyclonal Antibody for Human Cerebral dopamine neurotrophic factor
Monoclonal Antibody for Human Cerebral dopamine neurotrophic factor
Monoclonal Antibody for Human Cerebral dopamine neurotrophic factor
Monoclonal Antibody for Human Cerebral dopamine neurotrophic factor
Protein for Human Cerebral dopamine neurotrophic factor
Protein for Human Cerebral dopamine neurotrophic factor
Protein for Human Cerebral dopamine neurotrophic factor
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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more...
Nat. Genet.36:40-45(2004)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Spleen .
2.
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more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Testis .
4.
"Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TISSUE SPECIFICITY
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;INDUCTION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) OF 32-133;DISULFIDE BONDS